Discription

Drug Discovery is the process by which new molecules are discovered and now a days everybody is becoming aware of its level of importance especially in this era of COVID 19, which creates a possible anticipation of an increment in the demand for books related to screening methods of pharmacology. Pharmacological screening of drugs is a sequential testing of new chemical entities or extracts from biological material in isolated organs followed by test in whole experimental animals. Screening Methods in Pharmacology focuses on the methods for screening of moieties for pharmacological activities and discussions for organization of screening programs. This book envelops a descriptive approach detailed about CPCSEA, OECD and ICH guidelines that must be followed during screening of new drug moieties. It also provides a brief idea about bioassay and research methodology along with various experimental animal screening models for different diseases. This book shall serve as a reference guide for students of Pharmacy and life sciences graduates. Salient Features: 1. Beneficial for Pharmacy and life science graduates and research scholars. 2. Provides various experimental animal screening models for different diseases. 3. Gives special guidelines for animal use during experimental protocols. 4. Provides brief description about Bioassay Contents: 1. Regulations for Laboratory Animals Care and Ethical Requirements 2. Pharmacological Techniques for Evaluation of Drugs on Different Systems 3. Bioassay 4. Evaluation of Drugs acting on Autonomic Nervous System 5. Evaluation of Drugs Acting on Central Nervous System 6. Evaluation of Drugs Acting on Respiratory System 7. Evaluation of Drugs Acting on Eye 8. Evaluation of Drugs Acting on Cardiovascular System 9. Evaluation of Drugs Acting on Endocrine System 10. Evaluation of Drug Acting on Kidney 11. Miscellaneous 12. Transgenic Animals and other Genetically Modified Animal Models 13. Drug Toxicity and Safety Evaluation 14. Alternatives to Animal Screening Procedures 15. New Approaches in Drug Discovery 16. Research Methodology About the Authors: Surendra H. Bodakhe (M.Pharm., Ph.D, FIC) is currently working as Associate Professor of Pharmacology, at SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (Chhattisgarh). He has about 24 years of multifaceted experience in academics and research. He has to his name more than 60 publications in different journals of National and International repute, 4 books and one US patent. He is life member of APTI and Pharmacological Society of India. About 50 M. Pharmacy students and 6 Ph.D. research scholars have benefited from his guidance. He worked as co-coordinator in UGC-SAP project worth 90 lakhs. He has completed major and minor projects from various funding agencies like AYUSH (Govt of India), CGCOST. Parag Jain is currently working as Assistant Professor in CSIT, Bhilai, Chhattisgarh. He is having 6 years of experience in research and academics. He has published several research publications in peer reviewed national and international journals. He has several awards to his credit. Arin Bhattacharya is an Assistant Professor in JK college of Pharmacy, Bilaspur (Chhattisgarh). He has more than 5 years of experience in academics and research. He has to his credit several publication and books. He has also worked as Principal at AYUSH college of Pharmacy, Marwahi, Bilaspur. Jaya Shree (M.Pharm., Ph.D.) is an Assistant Professor in Rungta Institute of PharmaceuticalSciences (SRGI), Bhilai, (Chhattisgarh). She has more than 5 years of experience in academics and research. She has many publications in journals of National and International repute. She has completed her Ph.D (Pharmacy) from SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (Chhattisgarh). She has been a prominent speaker in webinars, national conferences and FDP programs. Her area of research interest is topical targeting of drugs for various ocular disorders. Amrita Singh is a Ph.D research scholar at SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (Chhattisgarh). She has received ICMR fellowship in the year 2018 for pursuing Ph.D. Her efforts in research have generated more than 10 peer reviewed international and national research papers. Her area of research interest is ocular pharmacology specifically linked to age related and metabolic disorders. She has presented several research papers in national and international conferences.