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APA Handbook of Neuropsychology, Volume 2 provides comprehensive foundational information on neuropsychology, identifies pressing research questions related to neuropsychological disorders and conditions, offers updates on methods to investigate these issues, and aims to shape the field’s future development. In Volume 2, Neuroscience and Neuromethods, the handbook focuses on neuroscience, brain imaging methods, and advanced statistical models needed to investigate the questions raised in Volume 1, as well as treatment paradigms to guide future interventions. Chapters aim to stimulate innovative assessment and intervention methods.  The chapters serve as an invaluable resource for the expanding field of neuropsychology. Clinicians, researchers, students, and scholars can use this handbook to gain a foundational understanding of neuropsychology and to further advance the field themselves.